LETTER TO THE EDITOR Diabetes mellitus and cancer in Werner syndrome
نویسندگان
چکیده
Onishi et al. recently reported here an association of diabetes mellitus (DM) with neoplasm type in newly identified patients with Werner syndrome (WS), an autosomal recessive cancer predisposition syndrome with features of premature aging that include a high risk of DM (Onishi et al. in Acta Diabetol 49(Suppl 1):259–260, 2012; Epstein et al. in Medicine 45:177–121, 1966). In contrast, we did not detect an association between DM and neoplasm type in an independent WS cohort we assembled to determine the histopathologic spectrum and type-specific risk of neoplasia in WS.
منابع مشابه
Letter to Editor: Positive predictive value of diabetes mellitus risk assessment
Diabetes mellitus (DM) is an important public health challenge [1 ].Different studies predicted that the frequency of diabetic patients will be increased to 642 million throughout the world by 2040 [2]. A notable percentage of diabetic patients are not aware of their disease (approximately 30% in Iran) [3]. Lag in the diagnosis of DM raises the expense of controlling disease and makes the progn...
متن کاملThe Importance of Examining Congenital Hypothyroidism in Connection with Congenital Heart Disease: Letter to Editor
Dear Editor-in-Chief: I read and enjoyed your stylish article, "Frequency of Congenital Cardiac Malformations in Neonates with Congenital Hypothyroidism", in relation to heart disease with hypothyroidism. As we know, one of the most commonly associated congenital hypothyroidism disorders is congenital heart disease, which has a significant effect on the recovery of pat...
متن کاملComparison of burning mouth syndrome prevalence between diabetes mellitus and hypothyroidism patients
Abstract Introduction: Due to the high prevalence of type 2 diabetes and hypothyroidism and the fact that the complication of burning mouth syndrome is seen in both of these diseases, we compared the frequency of burning mouth syndrome in patients with diabetes mellitus type 2 and patients with hypothyroidism referred to Rasht dental school in 1399. Materials and Methods:In this cross-section...
متن کاملWerner Syndrome and Diabetes Mellitus Accompanied by Adrenal Cortex Cancer
Werner syndrome is a rare genetic disease characterized by progeria, diabetes mellitus, cataracts and various types of malignancy. However, there are few reports showing adrenal cortex cancer in subjects with Werner syndrome. We herein report an extremely rare case of Werner syndrome accompanied by adrenal cortex cancer. Based on the data obtained from blood samples, computed tomography, magnet...
متن کامل